Ox-eye daisy spreads by seeds and by shallow, creeping rhizomes. It is not palatable to cattle and reduces the amount of quality pasture available for grazing.
Ox-eye daisy grows in soils low in Calcium and Phosphorus and high in Potassium, Magnesium, and Iron. It is an indicator of low organic matter and lack of beneficial microbial activity in the soil.
It is a typical grassland perennial wildflower, growing in a variety of plant communities including meadows and fields, under scrub and open-canopy forests, and in disturbed area.